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Ocular motor signatures of cognitive dysfunction in multiple sclerosis

The anatomical and functional overlap between ocular motor command circuitry and the higher-order networks that form the scaffolding for cognition makes for a compelling hypothesis that measures of ocular motility could provide a means to sensitively interrogate cognitive dysfunction in people with multiple sclerosis (MS). Such an approach may ultimately provide objective and reproducible measures of cognitive dysfunction that offer an innovative capability to refine diagnosis, improve prognostication, and more accurately codify disease burden. A further dividend may be the validation and application of biomarkers that can be used in studies aimed at identifying and monitoring preventative, protective and even restorative properties of novel neurotherapeutics in MS. This Review discusses the utility of ocular motor measures in patients with MS to characterize disruption to wide-ranging networks that support cognitive function.

via Nature Reviews Neurology : Nature Publishing Group.

Smart Vision Labs gets $6.1M for iPhone-enabled vision testing device

New York City-based Smart Vision Labs, which has developed a smartphone-based autorefractor for vision testing, raised $6.1 million in a round led by Techstars Ventures with participation from Heritage Group, Connectivity Capital, and Red Sea Ventures, according to TechCrunch. via mobihealthnews.

Ischemic Optic Neuropathies

A review article about diagnosis and management of ischemic optic neuropathies published in the latest issue of the NEJM via NEJM.